CRH

CRH
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3EHU, 3EHT, 1GOE
Dynodwyr
Cyfenwau	CRH, CRF, CRH1, corticotropin releasing hormone
Dynodwyr allanol	OMIM: 122560 HomoloGene: 599 GeneCards: CRH
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• hormone activity; • corticotropin-releasing hormone receptor 1 binding; • corticotropin-releasing hormone receptor 2 binding; • GO:0001948, GO:0016582 protein binding; • neuropeptide hormone activity; • signaling receptor binding; • corticotropin-releasing hormone activity;
Cydrannau o'r gell	• cytoplasm; • perikaryon; • varicosity; • extracellular region; • neuronal cell body; • extracellular space;
Prosesau biolegol	• adwaith i gocên; • response to immobilization stress; • positive regulation of cortisol secretion; • steroid metabolic process; • positive regulation of protein phosphorylation; • negative regulation of luteinizing hormone secretion; • positive regulation of cell death; • associative learning; • homeostasis yr ïon; • lung development; • diterpenoid metabolic process; • response to corticosterone; • female pregnancy; • negative regulation of norepinephrine secretion; • adrenal gland development; • synaptic transmission, dopaminergic; • negative regulation of cell death; • negative regulation of gene expression; • cellular response to dexamethasone stimulus; • positive regulation of corticosterone secretion; • response to estrogen; • locomotory exploration behavior; • regulation of NMDA receptor activity; • regulation of serotonin secretion; • positive regulation of calcium ion import; • glucocorticoid biosynthetic process; • GO:1901313 positive regulation of gene expression; • positive regulation of digestive system process; • genedigaeth; • response to pain; • positive regulation of circadian sleep/wake cycle, wakefulness; • positive regulation of cell population proliferation; • hypothalamus development; • learning or memory; • hormone-mediated apoptotic signaling pathway; • positive regulation of insulin secretion involved in cellular response to glucose stimulus; • response to ethanol; • inflammatory response; • negative regulation of circadian sleep/wake cycle, REM sleep; • response to ether; • positive regulation of behavioral fear response; • GO:0072468 signal transduction; • adwaith y celloedd i gocên; • long-term potentiation; • chemical synaptic transmission; • negative regulation of epinephrine secretion; • negative regulation of glucagon secretion; • G protein-coupled receptor signaling pathway; • negative regulation of systemic arterial blood pressure; • positive regulation of cAMP-mediated signaling; • positive regulation of corticotropin secretion;
	Sources:Amigo / QuickGO
Orthologau
	1392
	n/a
	ENSG00000147571
	n/a
	P06850
	n/a
	NM_000756
	n/a
	NP_000747
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CRH yw CRH a elwir hefyd yn Corticotropin releasing hormone (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q13.1.^[2]

[1] "Human PubMed Reference:".

[2] CRH - Cronfa NCBI

[1]

[2]